
Getz Pharma Pakistan (Pvt) Ltd
Sofosbuvir 400 mg
Inclusive of all taxes · Pack of 28 Tab
Frequently asked
Verified by Ailaaj Pharmacist
Licensed · DRAP-compliant
All products are sourced from DRAP-licensed suppliers and verified by our in-house pharmacists before dispatch.
Product Summary:
Sofiget 400 mg (Sofosbuvir) is an antiviral medicine used for the treatment of chronic Hepatitis C infection. It works by blocking the Hepatitis C virus (HCV) replication enzyme (NS5B polymerase), preventing the virus from multiplying in the body.
Who It's For:
Patients diagnosed with Chronic Hepatitis C (HCV infection) Adults requiring antiviral therapy as part of combination treatment Patients with or without liver cirrhosis (as advised by specialist)
Key Benefits:
Helps achieve sustained virologic response (SVR) → cure of HCV in many cases Stops viral replication Reduces risk of liver cirrhosis progression Lowers risk of liver failure and hepatocellular carcinoma (HCC) Well-tolerated with short treatment duration compared to older therapies
Primary Use:
Treatment of Chronic Hepatitis C infection
Also Used For:
Combination antiviral therapy for different HCV genotypes Patients with liver fibrosis or cirrhosis due to HCV Pre/post liver transplant HCV management (specialist-guided)
Who May Benefit:
Patients with confirmed Hepatitis C infection Individuals needing curative antiviral therapy Patients with liver disease due to HCV Those suitable for direct-acting antiviral regimens
Warnings:
Must always be used in combination therapy (not alone) Risk of hepatitis B reactivation in co-infected patients Monitor liver function during therapy May cause fatigue, headache, anemia (if combined with ribavirin) Dose adjustment may be required in severe renal impairment (depending on regimen)
Avoid If:
Known hypersensitivity to sofosbuvir Monotherapy use (ineffective alone) Pregnancy (only if combination therapy clearly required; avoid ribavirin-containing regimens in pregnancy) Severe drug interactions without specialist guidance
Interactions:
Amiodarone (risk of severe bradycardia) Rifampin / Rifabutin / Rifapentine (reduces efficacy) Carbamazepine, phenytoin, phenobarbital (reduce antiviral levels) St. John’s Wort (contraindicated) Other antiviral combinations (daclatasvir, ledipasvir, velpatasvir – used intentionally as regimen)
Headache, Fatigue, Nausea
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